| Special TNPSC 30 Dec 2007 |
| ... for regularising 153 Contract Medical Officers and 1352 Contract Medical Consultants
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| Books for TNPSC |
TargetPG TNPSC 1995 - 2003 Book
TargetPG TNPSC Interview Buster
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| TNPSC 2007 General |
|
TNPSC 2007 to be conducted for selecting 290 Assistant Surgeons
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| TNPSC 2005 |
|
TNPSC 2005 conducted on 16 Oct 2005
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| TNPSC 2003 |
| TNPSC 2003 conducted on 10 Oct 2003
|
Question and Answers of TNPSC Exam for Assistant Surgeons, held on October
16th, 2005
Series A : 51 to 100
51 In haemoglobin degradation, the first bile pigment formed is
a Bilirubin
b Biliverdin
c Bile acids
d Cholic acids
Reference : Chatterjee, 6th edition Page 477
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52 In Hepatic Jaundice with cholestasis urine contains
a high levels of conjugated bilirubin and urobilinogen
b high levels of
conjugated bilirubin and negligible urobilinogen
c high levels of unconjugated bilirubin and urobilinogen
d high levels of
unconjugated bilirubin and negligible urobilinogen
Reference : Chatterjee, 6th edition Page 591
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53 Following are the examples of unconjugated hyperbilirubinaemia except
a Gilbert's syndrome
b Dubin-Johnson syndrome
c Criglar-Najjar syndrome
d Lucey-Driscoll syndrome
Reference : Chatterjee, 6th edition Page 479
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54 The chloride shift involves
a K+ accompanying each bicarbonate that leaves the erythrocyte
b Carbonic acid
leaving the erythrocyte
c Bicarbonate leaving the erythrocyte in exchange for chloride
d Protons leaving
the erythrocyte for each CO2 that enters
Reference : Chaudhuri 2nd Edition Page 171 (also given in Ganong, but better
explained here)
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55 A patient with PCO2 of 60mm Hg and pPlasma bicarbonate of 25 mEq/L is likely
to have
a Acute metabolic acidosis
b Acute respiratory acidosis
c Compensated respiratory acidosis
d Chronic metabolic acidosis
Reference : Chaterjee 6th Edition Page 632
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56 Most circulating T3 and T4 are bound to
a Thyroxine-binding pre-albumin
b Thyroxine-binding globulin
c Gamma-globulins
d Thyroglobulin
Reference: Ganong, 22nd edition Table 18.1
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57 In patients with primary hypothyroidism which of the following laboratory
tests will be useful?
a Estimation oof T3
b Estimation of T4
c Estimation of TBC
d Detection of auto-antibodies
Reference Harrison, 15th edition Figure 330.5
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58 Which of the following is required for crystallization & storage of the
hormone, Insulin ?
a Mn
b Mg
c Ca
d Zn
Reference : Chaterjee 6th Edition Page 551
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59 Which of the following substances is present in high concentration in the
urine of patients with pheochromocytomas ?
a Epinephrine
b Dopamine
c Nor-Epinephrine
d 3-Methoxy 4-OH Mandelic acid
Reference : Robbins 7th Edition Page 1221
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60 Secondary Hypogonadism is due to
a Pituitary gonadotropin deficiency
b Pituitary corticotropin deficiency
c Testicular deficiency
d Ovarian deficiency
Reference Ganong, 22nd edition Page 445
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61 Hashimoto's disease is
a autoimmune disease of Thyroid
b excessive secreation of Adrenal cortex
c disorder of motor system of Brain
d none of these
Reference : Harrison 15th Edition Chapter 330
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62 Plasma cortisol level is maximal aroung
a 8-9 pm
b 2-3 pm
c 8 am
d Midnight
Reference : Harrison 16th Edition Page 2092
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63 Cushing syndrome is caused by
a Hyposecretion of growth hormone
b Hyposecretion of thyroxine
c Hypersecretion of cortisol
d Hypersecretion of Pituitary hormones
Reference : Harrison 16th Edition Page 2135
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64 Identify the wrong statement about cortisol :
a Secretion increased following injury
b Favours protein synthesis
c Enhances effects of antigen - antibody reactions
d Tends to lower blood
pressure
Reference : Harrison 16th Edition Page 2135
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65 Osmotic diuresis effect usually occurs in the
a Glomerulus
b Distal tubule
c Collecting duct
d Proximal tubule
Reference : KDTripathi 5th Edition 536 (please don't confuse the answer with
the other effects of mannitol)
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66 The following statements are true for gastrin except it
a stimulates secretion of HCI and pepsinogen
b decreases gastric antral mobility
c weakly stimulates gall bladder contraction
d increases resting pressure of
lower oesophageal sphincter
Reference Ganong, 22nd edition Page 485
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67 Commonest carcinoma in female is of
a uterus
b cervix
c breast
d ovary
Reference Page 302, Park, 18th edition
No cofusion
!!!. Consider this as wrong while calculating your answer irrespective of
whatever choice you have marked
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68 A cholagogue
a increases the rate of secretion of bile
b increases the contraction of gall
bladders
c increases the storage of bile in G.B.
d none of these
Reference Ganong, 22nd edition Page 503
Cholerectics increase the rate of secretion of bile
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69 Blood group antigen is
a carried by sex chromosomes
b attached to plasma proteins
c attached to haemoglobin molecule
d found in saliva
Reference : Ganong 22nd Edition Page 536
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70 All of the following cells arise from a common committed stem cell, except
a Red blood cells
b Platelets
c Granulocytes
d Lymphocytes
Reference : Ganong 22nd Edition page 517 and Page 621, Robbins, 7th edition
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71 Precursor of testosterone is
a Methyl testosterone
b Pregnenolone
c Aldosterone
d Cortisone
Reference Ganong, 22nd edition Page 429
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72 The principal steroid secreted by the fetal adrenal cortex is
a Progesterone
b Dehydro EPI androsterone
c Corticosterone
d Pregnenolone
Reference : Nelson 15th Edition Chapter 4
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73 Pneumothorax causes the following, except
a Reduced vital capacity
b Abnormal dullness to percussion on the affected side
c Reduction in residual volume
d Increased resonance on percussion on affected
side
Reference : Harrison 15th Edition Chapter 262
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74 Constriction of bronchial smooth muscle can result from the following, except
a Irritation of bronchial mucosa
b Cold stimulus to bronchial mucosa
c Stimulation of local beta adreno-receptors
d A decrease in PCO2 in bronchial
air
Reference : Harrison 15th Edition Chapter 252
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75 P-R interval in electrocardiogram denotes
a beginning of atrial depolarisation to end of ventricular depolarisation
b
beginning of atrial depolarisation to beginning of ventricular depolarisation
c end of atrial depolarisation to beginning of ventricular depolarisation
d end
of atrial depolarisation to end of ventricular depolarisation
Reference : Goldberger 3rd Edition page 13
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76 Work output of left ventricle is
a 5 times more than that of right
b same as that of right
c less than that of right
d 20 times more than that of right
Reference : Chaudhuri 2nd Edition Page 217.
Work =
Force x Distance
Work by
heart = Resistance x Cardiac Output (Stroke Volume)
Since,
Output of Both ventricles are equal and since the work is directly proportional
to the Resistance, the ration of work outputs will be the ration of the
resistances (blood pressure) of aorta and pulmonary artery, which is equal to 5
The
actual formula is W=Q.R + ((mv2)/2g)
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77 Positive chronotrophic effect mens
a Increase in heart rate
b Increase in conductivity
c Increase in force of contraction
d Increase in excitability
Reference Ganong, 22nd edition Page 572
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78 Red colour-blindness is called
a Deuteranopia
b Protanopia
c Protanomaly
d Deuteranomaly
Reference Ganong, 22nd edition Page 165
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79 During deep sleep there is a fall in
a Hand skin temperature
b Arterial PCO2
c Blood growth hormone/cortisol ration
d Metabolic rate
Reference : Harrison 15th Edition page 27
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80 In Brown-Sequard syndrome below the level of lesion, on the same side
a Loss of fine touch
b Loss of vibration sense
c Loss of stereognosis
d all of these
Reference : Datta Neuroanatomy Page 233
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81 Which of the following antiepileptic drugs is
used as alternative to lithium in mania and bipolar disorder ?
a Phenytoin
b Ethosuximide
c Carbamazepine
d vigabatrin
Reference KDTripathi, 5th edition Page 417,
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82 Long-term thlazide therapy causes hyperglycaemia by
a reducing insulin release
b interfering with glucose utilization in tissues
c increasing sympathetic activity
d increasing corticosteroid secretion
Reference KDTripathi, 5th edition
Page 507
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83 Drug of choice for radical cure of P. Vivax malaria is
a Chloroquine
b Quinine
c Primaquine
d Halofantrine
Reference : Park 18th Edition Page 208 and KDT, 5th edition Page 746,
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84 The rationale of giving beta blockers in angina is that they
a Dilate coronary arteries
b decrease the preload
c decrease the work of the heart
d increase O2 consumption
Reference KDTripathi, 5th edition Page 498
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85 Effects of the Glucocorticoids include all of the following, except
a Altered fat deposition
b Increased blood glucose
c Increased skin protein synthesis
d Inhibition of Leukotriene synthesis
Reference KDTripathi, 5th edition Page 257
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86 The side effect which limits the use of oral iron therapy is
a epigastric pain
b black stool
c staining of teeth
d metallic taste
Reference KDTripathi, 5th edition Page 550
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87 The agent that is effective against Helicobacter pylorii in peptic ulcer is
a Bismuth
b Pirenzepine
c Aluminium hydroxide
d Amoxycillin
Reference KDTripathi, 5th edition Page 598
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88 The antineoplastic drug used in psoriasis is
a Mitolane
b Mechlorethamine
c Melphalan
d Methotrexate
Reference KDTripathi, 5th edition Page 773
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89 Thyrotoxicosis can be treated with
a Glucocorticoids
b Methimazole
c Propyl thiouracil
d All of these
Reference KDTripathi, 5th edition Page 226 and Harrison 15th Edition Chapter 330
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90 The antiemetic drug with least extrapyramidal side effect is
a Metoclopramide
b Chlorpromazine
c Prochlorperazine
d Domperidone
Reference KDTripathi, 5th edition Page 604
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91 The
following are adverse reactions of nitrates, except
a Headache
b Postural hypotension
c Tolerance
d Bradycardia
Reference KDTripathi, 5th edition Page 489
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92 The following agents are used in acute myocardial infarction, except
a Fibrinolytics
b Aspirin
c Anti-fibrinolytics
d Heparin
Reference KDTripathi, 5th edition Page 501
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93 The approppriate drug for cardiogenic shock is
a Adrenaline
b Dopamine
c Isoprenaline
d Noradrenaline
Reference KDTripathi, 5th edition Page 112
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94 The most suitable tetracycline for use in a patient with impaired renal
function is
a Chlortetracycline
b Demeclocycline
c Oxytetracycline
d Doxycycline
Reference KDTripathi, 5th edition Page 671
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95 The drug which does not possess H2-histaminic receptor antagonistic action is
a Cimetidine
b Ranitidine
c Nizatidine
d
Loratidine
Reference KDTripathi, 5th edition Page 142, 588
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96 Which of the following hypolipidemic drugs causes constipation and bloating ?
a Colestipol
b Cholestyramine
c Both (A) and (B)
d None of these
Reference KDTripathi, 5th edition Page 579
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97 The anti-asthma drug which cannot be administered by inhalation is
a Theophylline
b Ipratropium Bromide
c Budesonide
d Terbutaline
Reference KDTripathi, 5th edition Page 200, 204
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98 Co-trimoxazole is a combination of
a Pyrimethamine and sulfodoxine
b Trimethoprim and sulfisoxazole
c Trimethoprim and sulfaphenazole
d Trimethoprim and sulfamethoxazole
Reference KDTripathi, 5th edition Page 644
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99 The drug used in prophylaxis for rheumatic fever is
a Procaine penicillin
b Benzyl penicillin
c Benzathine penicillin
d Cloxacillin
Reference KDTripathi, 5th edition Page 656
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100 The drug used for acute extra-pyramidal reaction to chlorpromazine is
a Physostigmine
b diphenhydramine
c propranolol
d metocolpramide
Reference KDTripathi, 5th edition Pages 144 and 397
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